Centre of Reconstructive Neuroscience
Study of alterations of the extracellular matrix in the central nervous system during pathological conditions
Alterations of the extracellular matrix (ECM) components during pathophysiological conditions in the central nervous system (CNS) can have significant consequences on the behaviour of neurons and glia. The aim of the project is to study the pathophysiological roles of the ECM in the CNS, particularly hyaluronic acid and chondroitin sulphate proteoglycans (CSPGs) molecules after various CNS insults, such as spinal cord injury, neurodegenerative diseases, during ageing or after various interventions. The role of the particular ECM molecules in the pathophysiology, inflammation and regeneration processes will be evaluated using biochemical and molecular biology methods.
The successful applicant should have an education in biochemistry, biology or medical science and have a good proficiency in English. Experience with molecular biology, biochemistry, animal work and surgery, is advantageous. The successful applicant will also have excellent interpersonal, communication and organizational skills and be highly-motivated with the ability to work independently and as part of the international team of NeuroRecon Centre.
Terms and place of employment
This position is available at the Institute of Experimental Medicine of the CAS, v.v.i.) in Prague, Czech Republic. The successful candidates will be part of the EU funded Centre of Reconstructive Neuroscience (NeuroRecon) research program. The Centre hosts an international collaborative research program between Institute of Experimental Medicine (Prague, CR) - John van Geest Centre for Brain Repair (University of Cambridge) - Faculty of Biological Sciences (University of Leeds). The position is available immediately as an initial fixed-term contract, with longer-term extension possible upon demonstrated proficiency.
Interested candidates should provide motivation letter and CV. For postdoc position, contacts to at least two independent professionals who can provide reference is required.
Your application must be submitted electronically to Dr. Sarka Kubinova (firstname.lastname@example.org). Dr Kubinova will provide additional information about the position as well.