Institute of Experimental Medicine CAS

Published 08. 07. 2021

In the current issue of the Biomedicines journal (IF=6.081) a review article by our young neuroscientist Kateřina Štěpánková from the Department of Neuroregeneration was published. Katka also designed the picture on the cover page of the mentioned journal. 

The article presents readers with the latest discoveries in gene therapy and neuroregeneration research. Spinal cord injury is a complicated condition with severe consequences for the patient, their family and society. The regenerative capacity of the spinal cord is severely limited. Effective and adequate treatment does not yet exist. Scientists are intensively searching for treatment options using gene therapy, which could potentially treat neurological and neurodegenerative diseases in the future. Experimental treatments in animal models use specially developed viral vectors (derived from lentiviruses or adeno-associated viruses) through which specific genes are integrated into the organism. These genes are transcribed, and their gene products trigger the repair process.

You can find more information in the published article:
Biomedicines | Free Full-Text | Planet of the AAVs: The Spinal Cord Injury Episode (mdpi.com)