Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

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Nanoparticles and stem cells: A new direction in the treatment of damaged corneas

PublicationResearch Published on 25. 06. 2025 Reading time: 2 minutes

The gut microbiome as the key to early cancer diagnosis: Czech scientists are participating in the development of a rapid diagnostic test for colorectal cancer

PublicationResearch Published on 23. 06. 2025 Reading time: 2 minutes

Klára Vokáčová has been awarded the Otto Wichterle Award

Award Published on 12. 06. 2025 Reading time: 2 minutes

Why do brain cancer cells steal mitochondria? New research by IBT CAS and IEM CAS reveals the metabolic dependence of cancer cells

PublicationResearch Published on 28. 05. 2025 Reading time: 3 minutes

A new TUBE study shows that the impact of diesel emissions on brain cells depends on the engine technology

PublicationResearch Published on 26. 05. 2025 Reading time: 2 minutes

A new study from the EXREGMED project shows that stem cell pre-treatment can fundamentally affect their properties

PublicationResearch Published on 23. 05. 2025 Reading time: 1 minute
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Events

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02. 09. 2025 - 11. 09. 2025

NanoEnviCz: Summer School for Nanomaterials 2025

Professional EventsWorkshop

04. 09. 2025

Institutional Seminar Series 9/2025

Professional EventsSeminar

08. 09. 2025 - 12. 09. 2025

Advanced Course on Preclinical Imaging

CourseCzech-BioimagingMicroscopy

06. 11. 2025

Institutional Seminar Series 11/2025

Professional EventsSeminar

12. 11. 2025 - 14. 11. 2025

Introduction to Programming for Image Processing

CourseCzech-BioimagingMicroscopy

04. 12. 2025

Institutional Seminar Series 12/2025

Professional EventsSeminar
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2023–2024 (pdf, 27610 kB)
  • 1975 Established
  • 219 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

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Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

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Latest Publications

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Single-Atom Colloidal Nanorobotics Enhanced Stem Cell Therapy for Corneal Injury Repair

 Department of Toxicology and Molecular Epidemiology AutořiJu X.Javorková E.Michalička J.Pumera M. Published on 2025 Metadata ACS Nano. 2025 May 27;19(20):19095-19115. doi: 10.1021/acsnano.4c18874. Epub 2025 May 13.

Functional mitochondrial respiration is essential for glioblastoma tumour growth

 Department of Cellular Neurophysiology AutořiBrisudova P.Stojanovic D.Novak J.Nahacka Z.Lopes Oliveira G.Vaňátko O.Dvorakova S.Endaya B.Truksa J.Kubísková M.Foltýnová A.Jirak D.Jirat-Ziolkowska N.Kucera L.Chalupsky K.Klima K.Prochazka J.Sedlacek R.Mengarelli F.Orlando P.Tiano L.Oliveira P. J.Grasso C.Berridge M. V.Zobalova R.Anděrová M.Neuzil J. Published on 2025 Metadata Oncogene . 2025 May 5. doi: 10.1038/s41388-025-03429-6. Online ahead of print.

Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury

 Department of Neuroregeneration Department of Auditory Neuroscience AutořiŠtěpánková K.Smejkalová B.Urdzíková-Machová L.Havelíková K.de Winter F.Suchánková S.Verhaagen J.Herynek V.Tureček R.Kwok J. C. F.Fawcett J.Jendelová P. Published on 2025 Metadata Acta Neuropathol Commun . 2025 May 2;13(1):89. doi: 10.1186/s40478-025-01995-0.

Transient crossed aphasia associated with the right SMA syndrome following the resection of oligodendroglioma: A case report

 Department of Neuroregeneration AutořiKrůpa P.Adamkov J.Lednova V.Kasparova P.Cesak T. Published on 2025 Metadata Journal of Neurolinguistics, Volume 74, May 2025, 101244, https://doi.org/10.1016/j.jneuroling.2024.101244

Traffic-related ultrafine particles influence gene regulation in olfactory mucosa cells altering PI3K/AKT signaling

 Department of Toxicology and Molecular Epidemiology AutořiMussalo L.Afonin A. M.Závodná T.Krejčík Z.Hoňková K.Fayad C.Shahbaz M. A.Kalapudas J.Penttilä E.Löppönen H.Koivisto A. M.Malm T.Topinka J.Jalava P.Lampinen R.Kanninen K. M. Published on 2025 Metadata Environ Int . 2025 May:199:109484. doi: 10.1016/j.envint.2025.109484. Epub 2025 Apr 17.

The role of cytokine licensing in shaping the therapeutic potential of wharton's jelly MSCs: metabolic shift towards immunomodulation at the expense of differentiation

 Department of Neuroregeneration Department of Toxicology and Molecular Epidemiology AutořiRohulska O.Vavřinová E.Vackova I.Havelková J.Gotvaldova K.Abaffy P.Kubinova S.Šíma M.Rössner P.Bacakova L.Jendelová P.Smolkova K.Petrenko Y. Published on 2025 Metadata Stem Cell Res Ther . 2025 Apr 20;16(1):199. doi: 10.1186/s13287-025-04309-2.

Mendelian randomization study of sleep traits and risk of colorectal cancer

 Department of Molecular Biology of Cancer AutořiDimopoulou O.Fuller H.Richmond R. C.Bouras E.Hayes B.Dimou N.Murphy N.Brenner H.Gsur A.Le Marchand L.Moreno V.Pai R. K.Phipps A. I.Um C. Y.van Duijnhoven F. J. B.Vodička P.Martin R. M.Platz E. A.Gunter M. J.Peters U.Lewis S. J.Cao Y.Tsilidis K. K. Published on 2025 Metadata Sci Rep . 2025 Apr 18;15(1):13478. doi: 10.1038/s41598-024-83693-w.

Combined strategy of α 9-integrin transduction and AEIDGIEL peptide-functionalized fibrin gel biomaterials to promote mature DRG neurite growth

 Department of Neuroregeneration AutořiCimpean A.Roll L.Reinhard J.Kwok J. C. F.Faissner A.de Winter F.Fawcett J.Jendelová P. Published on 2025 Metadata Front Cell Neurosci . 2025 Apr 1:19:1568004. doi: 10.3389/fncel.2025.1568004. eCollection 2025.

Hybrid fibres: a new path in tissue regeneration

 Department of Neuroregeneration AutořiKulhánková J.Hobbs Ch. J.Nikendey Holubová B.Erben J.Rysová M.Musílková J.Svobodová L.Romanyuk N.Máková V. Published on 2025 Metadata J Mater Sci Mater Med . 2025 Mar 26;36(1):29. doi: 10.1007/s10856-025-06875-6.
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