Institute of Experimental Medicine of the CAS

Biomedical research towards effective diagnosis and treatment

About Us

Research

Study & Careers


News

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From stars to DNA: Toxicologist Kateřina Hoňková will be a guest at a panel discussion at the famous festival Colours of Ostrava

InvitationPopularisation of Science Published on 17. 07. 2025 Reading time: 2 minutes

New models for fighting pancreatic cancer: How science is testing breakthrough therapies

PublicationResearch Published on 15. 07. 2025 Reading time: 3 minutes

Quality control of NMDA receptors: the influence of the ligand-binding domain

PublicationResearch Published on 09. 07. 2025 Reading time: 3 minutes

Nanoparticles and stem cells: A new direction in the treatment of damaged corneas

PublicationResearch Published on 25. 06. 2025 Reading time: 2 minutes

The gut microbiome as the key to early cancer diagnosis: Czech scientists are participating in the development of a rapid diagnostic test for colorectal cancer

PublicationResearch Published on 23. 06. 2025 Reading time: 2 minutes

Klára Vokáčová has been awarded the Otto Wichterle Award

Award Published on 12. 06. 2025 Reading time: 2 minutes
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Events

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02. 09. 2025 - 11. 09. 2025

NanoEnviCz: Summer School for Nanomaterials 2025

Professional EventsWorkshop

04. 09. 2025

Institutional Seminar Series 9/2025

Professional EventsSeminar

02. 10. 2025

Institutional Seminar Series 10/2025

Institutional SeminarProfessional Events

06. 11. 2025

Institutional Seminar Series 11/2025

Professional EventsSeminar

12. 11. 2025 - 14. 11. 2025

Introduction to Programming for Image Processing

CourseCzech-BioimagingMicroscopy

04. 12. 2025

Institutional Seminar Series 12/2025

Professional EventsSeminar
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About Us

We are a renowned centre of basic biomedical research in the Czech Republic and worldwide. Our projects are focused on biomedical challenges, such as finding effective diagnostic markers and treatment of serious diseases associated with ageing of the human population (neurodegeneration, trauma, ischemia, musculoskeletal disorders, cancer and degenerative changes in vision and hearing). We also seriously consider the impact of environmental pollution on human health.

  • We are a proud holder of the “HR Excellence in Research” and “Ethnic Friendly Employer” awards.
  • We are a member of the Euro-BioImaging, Czech-BioImaging, EATRIS, and NanoEnviCz infrastructures.
More information
Annual Brochure 2023 – 2024 (pdf, 28616 kB)
  • 1975 Established
  • 219 Employees
  • 46 Projects
  • 86 Publications (2024)

Research Departments and Centres

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Department of Auditory Neuroscience

Research department

Head of the Department

Rostislav Tureček

Department of Tissue Engineering

Research Department

Head of the Department

Eva Filová

Department of Molecular Biology of Cancer

Research Department

Head of the Department

Veronika Vymetálková

Department of Developmental Biology

Research Department

Head of the Department

Ondřej Machoň

Department of Functional Organisation of Biomembranes

Research Department

Head of the Department

Jan Malínský

Department of Neuroregeneration

Research Department

Head of the Department

Pavla Jendelová

Department of Toxicology and Molecular Epidemiology

Research Department

Head of the Department

Pavel Rössner

Department of Cell Nucleus Plasticity

Research Department

Head of the Department

Helena Fulková

Centre for Reconstructive Neuroscience

Research Centre

Head of the Research Centre

James Fawcett

Department of Cellular Neurophysiology

Research Department

Head of the Department

Miroslava Anděrová

Department of Neurochemistry

Research Department

Head of the Department

Martin Horák

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Latest Publications

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Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer

 Department of Molecular Biology of Cancer AutořiSimoes A. R.Carlés González S.Lopez-Doldan M. C.Duran G.Fernández-Montes A.Fernandez M. P.Salgado Fernandez M.Garcia Mata J.Paez D.Riera P.Guino E.Lopez-Fernandez L.Garcia de Santiago B.López Aspiroz E.Rojas A.Castells A.Castellvi-Bel S.Ruiz Ponte C.Vymetálková V.Carracedo A.Fernandez-Rozadilla C. Published on 2025 Metadata Br J Pharmacol . 2025 Jul 7. doi: 10.1111/bph.70051. Online ahead of print.

Biomimetic Tumour Model Systems for Pancreatic Ductal Adenocarcinoma in Relation to Photodynamic Therapy

 Department of Molecular Biology of Cancer AutořiSmith O. M.Lintern N.Tian J.Mesquita B. M.Oliveira S.Vymetálková V.Prakash J.Smith A. M.Jayne D. G.Heger M.Khaled Y. S.Photodynamic Therapy Study Group Published on 2025 Metadata Int J Mol Sci . 2025 Jul 2;26(13):6388. doi: 10.3390/ijms26136388.

Distinct Regulation of Early Trafficking of the NMDA Receptors by the Ligand-Binding Domains of the GluN1 and GluN2A Subunits

 Department of Neurochemistry AutořiNetolický J.Baráčková P.Misiachna A.Kolcheva M.Řeháková K.Hemelíková K.Kortus S.Langore E.Doderović J.Ladislav M.Korabecny J.Otyepka M.Srejber M.Horák M. Published on 2025 Metadata J Neurosci . 2025 Jun 25;45(26):e0226242025. doi: 10.1523/JNEUROSCI.0226-24.2025.

Single-Atom Colloidal Nanorobotics Enhanced Stem Cell Therapy for Corneal Injury Repair

 Department of Toxicology and Molecular Epidemiology AutořiJu X.Javorková E.Michalička J.Pumera M. Published on 2025 Metadata ACS Nano. 2025 May 27;19(20):19095-19115. doi: 10.1021/acsnano.4c18874. Epub 2025 May 13.

Functional mitochondrial respiration is essential for glioblastoma tumour growth

 Department of Cellular Neurophysiology AutořiBrisudova P.Stojanovic D.Novak J.Nahacka Z.Lopes Oliveira G.Vaňátko O.Dvorakova S.Endaya B.Truksa J.Kubísková M.Foltýnová A.Jirak D.Jirat-Ziolkowska N.Kucera L.Chalupsky K.Klima K.Prochazka J.Sedlacek R.Mengarelli F.Orlando P.Tiano L.Oliveira P. J.Grasso C.Berridge M. V.Zobalova R.Anděrová M.Neuzil J. Published on 2025 Metadata Oncogene . 2025 May 5. doi: 10.1038/s41388-025-03429-6. Online ahead of print.

Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury

 Department of Neuroregeneration Department of Auditory Neuroscience AutořiŠtěpánková K.Smejkalová B.Urdzíková-Machová L.Havelíková K.de Winter F.Suchánková S.Verhaagen J.Herynek V.Tureček R.Kwok J. C. F.Fawcett J.Jendelová P. Published on 2025 Metadata Acta Neuropathol Commun . 2025 May 2;13(1):89. doi: 10.1186/s40478-025-01995-0.

Transient crossed aphasia associated with the right SMA syndrome following the resection of oligodendroglioma: A case report

 Department of Neuroregeneration AutořiKrůpa P.Adamkov J.Lednova V.Kasparova P.Cesak T. Published on 2025 Metadata Journal of Neurolinguistics, Volume 74, May 2025, 101244, https://doi.org/10.1016/j.jneuroling.2024.101244

Traffic-related ultrafine particles influence gene regulation in olfactory mucosa cells altering PI3K/AKT signaling

 Department of Toxicology and Molecular Epidemiology AutořiMussalo L.Afonin A. M.Závodná T.Krejčík Z.Hoňková K.Fayad C.Shahbaz M. A.Kalapudas J.Penttilä E.Löppönen H.Koivisto A. M.Malm T.Topinka J.Jalava P.Lampinen R.Kanninen K. M. Published on 2025 Metadata Environ Int . 2025 May:199:109484. doi: 10.1016/j.envint.2025.109484. Epub 2025 Apr 17.

The role of cytokine licensing in shaping the therapeutic potential of wharton's jelly MSCs: metabolic shift towards immunomodulation at the expense of differentiation

 Department of Neuroregeneration Department of Toxicology and Molecular Epidemiology AutořiRohulska O.Vavřinová E.Vackova I.Havelková J.Gotvaldova K.Abaffy P.Kubinova S.Šíma M.Rössner P.Bacakova L.Jendelová P.Smolkova K.Petrenko Y. Published on 2025 Metadata Stem Cell Res Ther . 2025 Apr 20;16(1):199. doi: 10.1186/s13287-025-04309-2.
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